Address:

Universitetsparken 2

2100 Copenhagen

Tel: +45 35 33 60 55

e-mail: kak1(at)farma.ku.dk

 

Professional Interests:

CNS control of states of arousal and sleep

Neurobiology of drug addiction

 

 

Post Graduate Appointments  

New York Medical College

University of British Columbia

 


Graduate Degrees:  

Ph.D. in Neuroscience, University of California at Los Angeles

B.A. Marine Biology and Cinematic Studies, University of California at Berkeley

 

Selected Bibliography:

Leonard CS, Kalogiannis M and Kohlmeier KA (2011) Hypocretin/orexin receptor functions in mesopontine systems regulating sleep, arousal and cataplexy. In: Narcolepsy: Pathophysiology, Diagnosis and Treatment  eds. Basetto C, Scammell T and Baumann C.

Kohlmeier KA and Kristiansen U  (2010) GABAergic actions on cholinergic laterodorsal tegmental neurons: implications for control of behavioral state.  Neuroscience. 171(3):812-879.

Ishibashi M, Leonard CS and Kohlmeier KA (2009) Nicotinic activation of laterodorsal tegmental neurons: implications for nicotine addiction.  Neuropsychopharmacology, 34(12):2529-47. (Chosen as a featured article in MDLinx:  http://www.mdlinx.com/pharmacistlinx/news-article.cfm/2812129)

Kohlmeier KA, Watanabe S, Tyler CJ, Burlet S and Leonard CS  (2008)  Dual actions of Hypocretin/Orexin on laterodorsal tegmentum and dorsal raphe neurons. Journal of Neurophysiology. 100(4):2265-81.

Kohlmeier KA, Soja PJ and Kristensen MP  (2006)  Disparate cholinergic currents in rat principal trigeminal sensory nucleus neurons mediated by M1 and M2 receptors: a possible mechanism for selective gating of afferent sensory neurotransmission. European Journal of Neuroscience, 23:3245-3258.

Kohlmeier KA and Leonard CS (2006)  Transmitter modulation of spike-evoked calcium transients in arousal related-neurons: Muscarinic inhibition of SNX-482 sensitive calcium influx. European Journal of Neuroscience, 23:1151-1162.

Kohlmeier KA, Inoue T and Leonard CS (2004) Hypocretin/peptide signaling in the ascending arousal system: regulation of intracellular calcium in the dorsal raphe and laterodorsal tegmentum.  Journal of Neurophysiology, 92:221-235.

Willie JT, Chemelli RM, Sinton CM, Tokita S, Williams SC, Kisanuki Y, Marcus JN, Lee C, Elmquist JK, Kohlmeier KA, Leonard CS, Richardson JA, Hammer RE and Yanagisawa M  (2003)  Distinct Narcolepsy Syndromes in Orexin Receptor-2 and Orexin Null Mice. Molecular Genetic Dissection of Non-REM and REM Sleep Regulatory Processes.  Neuron, 38(5):715-30.

 

Teaching:

B-25 General Pharmacology

B-25(2) Laboratory Exercises in General Pharmacology

B-26 Organ-Related Pharmacology

B-375 Experimental In Vitro pharmacology

Within the Programme for a MSc in Pharmaceutical Sciences (Cand.scient i lægemiddelvidenskab)

Principles of Pharmacology

Pharmacology: From Physiology to Therapy (Course Chair)

 

Committee and Society Memberships:

Committee Member, Sleep Research Society, Research Committee 2007-Present

Society for Neuroscience, Member

Sleep Research Society, Member